Atherogenic index of plasma combined with waist circumference and body mass index to predict metabolic-associated fatty liver disease

doi:10.3748/wjg.v28.i36.5364

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Sep 28, 2022 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2022; 28(36): 5364-5379
Published online Sep 28, 2022. doi: 10.3748/wjg.v28.i36.5364

Table 1 Baseline characteristics of the study subjects

Variable	Non-MAFLD, n = 352	MAFLD, n = 512	Statistics¹	P value
Demographics
Sex			χ² = 14.020	< 0.001
Male	230 (65.3)	394 (77.0)
Female	122 (34.7)	118 (23.0)
Age in yr	37.750 ± 10.736	41.240 ± 10.852	t = -4.634	< 0.001
Age ≥ 40 yr	115 (32.7)	254 (49.6)	χ² = 24.461	< 0.001
Age < 40 yr	237 (67.3)	258 (40.4)
Smoking history	81 (23.0)	174 (34.0)	χ²= 12.073	< 0.001
Drinking history	76 (21.6)	145 (28.3)	χ²= 4.962	0.027
Anthropometrics
WC in cm	86.240 ± 9.893	96.790 ± 8.618	t = -16.219	< 0.001
BMI in kg/m²	24.436 ± 3.169	28.028 ± 3.221	t = -16.228	< 0.001
SBP in mmHg	125.880 ± 14.883	133.610 ± 16.859	t = -6.908	< 0.001
DBP in mmHg	77.500 ± 11.658	82.950 ± 12.525	t = -6.461	< 0.001
Laboratory tests
ALT in U/L	21.0 (15.0, 30.0)	34.0 (24.0, 54.0)	Z = -12.276	< 0.001
AST in U/L	19.0 (17.0, 23.0)	23.0 (19.0, 29.0)	Z = -9.058	< 0.001
TC in mmol/L	4.539 ± 0.847	4.783 ± 0.902	t = -4.104	< 0.001
TG in mmol/L	1.1 (0.7, 1.5)	1.8 (1.3, 2.6)	Z = -13.650	< 0.001
HDL-C in mmol/L	1.351 ± 0.283	1.191 ± 0.256	t = 8.321	< 0.001
LDL-C in mmol/L	2.645 ± 0.708	2.906 ± 0.884	t = -4.568	< 0.001
FBG in mmol/L	5.2 (4.9, 5.4)	5.4 (5.1, 5.9)	Z = -7.637	< 0.001
SUA in μmol/L	332.722 ± 86.289	377.836 ± 85.859	t = -7.590	< 0.001
AIP	-0.11 (-0.30, 0.08)	0.20 (0.03, 0.39)	Z = -14.006	< 0.001

¹Comparison of significant differences between the two groups; χ² value calculated by the χ² test; Z value calculated by the Mann-Whitney U test; t value calculated by the independent samples t test. Data are presented as median and interquartile range, mean and standard deviation or frequency (percentage). MAFLD: Metabolic-associated fatty liver disease; WC: Waist circumference; BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; FBG: Fasting blood glucose; SUA: Serum uric acid; AIP: Atherogenic index of plasma.

Citation: Duan SJ, Ren ZY, Zheng T, Peng HY, Niu ZH, Xia H, Chen JL, Zhou YC, Wang RR, Yao SK. Atherogenic index of plasma combined with waist circumference and body mass index to predict metabolic-associated fatty liver disease. World J Gastroenterol 2022; 28(36): 5364-5379
URL: https://www.wjgnet.com/1007-9327/full/v28/i36/5364.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i36.5364