Histopathological assessment of the microscopic activity in inflammatory bowel diseases: What are we looking for?

doi:10.3748/wjg.v28.i36.5300

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2022; 28(36): 5300-5312
Published online Sep 28, 2022. doi: 10.3748/wjg.v28.i36.5300

Table 2 Simplified Geboes score

Simplified Geboes score
Grade 0: No inflammatory activity	0.0 No abnormalities; 0.1 Presence of architectural changes; 0.2 Presence of architectural changes and chronic mononuclear cell infiltrate
Grade 1: Basal plasma cells	1.0 No increase; 1.1 Mild increase; 1.2 Marked increase
Grade 2A: Eosinophils in lamina propria	2A.0 No increase; 2A.1 Mild increase; 2A.2 Marked increase
Grade 2B: Neutrophils in lamina propria	2B.0 No increase; 2B.1 Mild increase; 2B.2 Marked increase
Grade 3: Neutrophils in epithelium	3.0 None; 3.1 < 50% crypts involved; 3.2 > 50% crypts involved
Grade 4: Epithelial injury (in crypt and surface epithelium)	4.0 None; 4.1 Marked attenuation; 4.2 Probable crypt destruction: probable erosions; 4.3 Unequivocal crypt destruction: unequivocal erosion; 4.4 Ulcer or granulation tissue

Citation: Fabian O, Bajer L. Histopathological assessment of the microscopic activity in inflammatory bowel diseases: What are we looking for? World J Gastroenterol 2022; 28(36): 5300-5312
URL: https://www.wjgnet.com/1007-9327/full/v28/i36/5300.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i36.5300