Dynamic blood presepsin levels are associated with severity and outcome of acute pancreatitis: A prospective cohort study

Figure 1 Association between dynamic blood presepsin levels and severity of acute pancreatitis. A: Presepsin levels on days 1, 3, 5 and 7 after admission in mild (M), moderately severe (MS) and severe (S) acute pancreatitis (AP). ^aP < 0.05 vs M AP; ^bP < 0.01 vs M AP; ^cP < 0.001 vs M AP; ^dP < 0.05 vs MS AP; ^eP < 0.01 vs MS AP; B: Clearance rate of presepsin in patients with M and non-mild (NM) (MS and S) AP; ^fP < 0.05 vs MS and S AP; C: Time-specific concentrations of presepsin in patients with M and NM AP; ^gP < 0.001 vs M AP; D: Correlation between presepsin and organ failure in patients with AP. ^hP < 0.05 vs no organ failure; ⁱP < 0.01 vs no organ failure; ^jP < 0.001 vs no organ failure; ^kP < 0.05 vs 1 organ failure. Lines denote median values, boxes represent 25^th to 75^th percentiles, and whiskers indicate the range.