Ji-Chuan decoction ameliorates slow transit constipation via regulation of intestinal glial cell apoptosis

Figure 2 Histological changes in the distal colon. A: Distal colon of the healthy control group; B: In the distal colons of mice in the slow transit constipation group, more severe inflammatory infiltration was observed; C: In the distal colons of mice in the low-dose Ji-Chuan decoction (JCD) treatment group, more severe inflammatory infiltration was observed; D: In the distal colon of mice in the middle-dose JCD group, there was reduced inflammation; E: High-dose JCD treatment restored the normal tissue morphology of the distal colon of constipated mice; F: Mosapride treatment restored the normal tissue morphology of the distal colon of constipated mice. Sections were observed at 400 × using a light microscope.