Diagnosis, treatment, and current concepts in the endoscopic management of gastroenteropancreatic neuroendocrine neoplasms

Figure 3 Pancreatic neuroendocrine neoplasm. A: Endoscopic ultrasound revealed a 15 mm hypoechoic lesion of the pancreas; B: Stained immunohistochemically for chromogranin showing diffuse and strong positivity (original magnification 400 ×), consistent with a poorly differentiated neuroendocrine tumor infiltrating the entire thickness of the muscle tissue to the head of the pancreas; C: The proliferation index (Ki-67) < 20%.