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©The Author(s) 2022.
World J Gastroenterol. Sep 14, 2022; 28(34): 5076-5085
Published online Sep 14, 2022. doi: 10.3748/wjg.v28.i34.5076
Published online Sep 14, 2022. doi: 10.3748/wjg.v28.i34.5076
Table 2 Clinical features and immunosuppression regimen of 16 transplant patients with gastrointestinal stromal tumor
Ref. | Age (yr)/sex | Transplanted organ | Time from transplantation to diagnosis | Location of primitive GIST | Metastasis at diagnosis | Evolution/delay | Immunosuppression before diagnosis | Immunosuppression after diagnosis | |
Agaimy and Wünsch[11] | 59/F | Kidney | 40 mo | Stomach | No | Relapse 68 mo | Not described | Not described | |
Agaimy and Wünsch[11] | 58/F | Kidney | 96 mo | Small bowel | No | Not described | Not described | Not described | |
Saidi et al[19] | 54/M | Liver | 11 mo | Colon | No | Not described | Tac, Aza | Not described | |
Camargo et al[22] | 64/M | Liver | 7 mo | Perineum | No | Not described | Tac, mycophenolate sodium | Not described | |
Tu et al[18] | 57/F | Kidney | 6 mo | Pelvis | No | Not described | Steroids, CsA, MMF | CsA and MMF at half dosage; rapamycin-containing regimensteroids withdrawn | |
Mulder et al[12] | 72/M | Kidney | 21 yr | Stomach | No | Peritoneal metastasis/24 mo | Steroids, CsA | Steroids, CsA (60% reduction in dosage) | |
Mrzljak et al[20] | 53/M | Liver | 12 mo | Jejunum | No | No | Tac, MMF | Same | |
Cimen et al[13] | 46/F | Kidney | 18 yr | Stomach | No | Not described | Steroids, CsA, Aza | Same with reduced dosage of CsA | |
Cheung et al[14] | 64/M | Kidney | 2 yr | Stomach | No | Yes/2 yr | Steroids, Tac, MMF | Steroids, Tac (reduced dosage), everolimus | |
Cheung et al[14] | 48/M | Kidney | 1 yr | Mesentery | Multiple tumors | No | CsA, MMF | CsA withdrawal, sirolimus introduction | |
Patiño et al[15] | 23/F | Kidney | 13 yr | Stomach | No | Local relapse/3 yr | Steroids, Tac, MMF | Not described | |
Xie et al[21] | 60/M | Liver | 11 mo | Stomach | No | No | Tac, sirolimus, MMF | Same | |
Elkabets et al[17] | 74/M | Kidney | 7 yr | Stomach | No | No | Steroids, CsA, MMF | Switch CsA to mTOR inhibitor | |
Takahashi et al[16] | 64/M | Kidney | 72 mo | Small bowel | No | No | Steroids, CsA, MMF | Stop CsA | |
Stammler et al | 60/M | Kidney | 5 mo | Stomach | No | No | Steroids, Tac, MMF | Switch MMF to belatacept | |
Stammler et al | 64/M | Kidney | 51 mo | Stomach | No | Yes/23 mo | Steroids, CsA, MMF | Switch CsA to Tac |
- Citation: Stammler R, Anglicheau D, Landi B, Meatchi T, Ragot E, Thervet E, Lazareth H. Gastrointestinal tumors in transplantation: Two case reports and review of literature . World J Gastroenterol 2022; 28(34): 5076-5085
- URL: https://www.wjgnet.com/1007-9327/full/v28/i34/5076.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i34.5076