Previous hepatitis B viral infection–an underestimated cause of pancreatic cancer

doi:10.3748/wjg.v28.i33.4812

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Sep 7, 2022 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Gastroenterol. Sep 7, 2022; 28(33): 4812-4822
Published online Sep 7, 2022. doi: 10.3748/wjg.v28.i33.4812

Table 2 Study population characteristics

	PDAC, n = 60	Control, n = 70
Age in yr, Me (25%-75%)	64 (59-69)	62 (58-65)
Race/Ethnicity
White/Caucasian, n (%)	56 (93.3)	65 (92.9)
Asian, n (%)	4 (6.7)	5 (7.1)
Females, n (%)	33 (55.0)	45 (64.3)
Anti-HBc (total), n (%)	18 (30.0)^a	9 (12.9)
Anti-HBc + anti-HBs, n (%)	8 (13.3)	5 (7.1)
Anti-HBc (only), n (%)	10 (16.7)	4 (5.7)
HBV DNA (blood and/or pancreatic tissue), n (%¹)	8 (44.4)^a	0
HBV DNA (pancreatic tissue only), n (%¹)	6 (33.3)^a	0

^aP < 0.05 pancreatic ductal adenocarcinoma vs control (Yates corrected χ²).

¹The percentage is according to the number of anti-hepatitis B core antigen-positive cases.

PDAC: Pancreatic ductal adenocarcinoma; Me: Median; HBV: Hepatitis B virus; HBc: Hepatitis B core antigen; HBs: Hepatitis B surface antigen.

Citation: Batskikh S, Morozov S, Dorofeev A, Borunova Z, Kostyushev D, Brezgin S, Kostyusheva A, Chulanov V. Previous hepatitis B viral infection–an underestimated cause of pancreatic cancer. World J Gastroenterol 2022; 28(33): 4812-4822
URL: https://www.wjgnet.com/1007-9327/full/v28/i33/4812.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i33.4812