Effects of Granule Dendrobii on chronic atrophic gastritis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats

Figure 2 Pathological changes of gastric mucosa after treatment. A: Improved histopathology of gastric mucosa; B: Reduced inflammation of gastric mucosa; C and D: Treatment with Granule Dendrobii improved the thickness and gland number of gastric mucosa in rats with chronic atrophic gastritis; E and F: Treatment with Granule Dendrobii increased the number of chief cells and parietal cells in gastric mucosa in rats with chronic atrophic gastritis; G: Treatment with Granule Dendrobii improved intestinal metaplasia of gastric mucosa in rats with chronic atrophic gastritis. Data were evaluated for statistical significance by one-way ANOVA, least significant difference test and Dunnett T3 test, and are represented as follows: ^aP < 0.05 and ^bP < 0.01 vs chronic atrophic gastritis with no-treatment group. GD High: Chronic atrophic gastritis rats treated with a high dosage of Granule Dendrobii; GD Medium: Chronic atrophic gastritis rats treated with a medium dosage of Granule Dendrobii; GD Low: Chronic atrophic gastritis rats treated with a low dosage of Granule Dendrobii; YWS: Chronic atrophic gastritis rats treated with Yangweishu; CAG: Chronic atrophic gastritis.