Anti-tumour activity and toxicological studies of combination treatment of Orthosiphon stamineus and gemcitabine on pancreatic xenograft model

Figure 3 Tissue sections of mice liver stained with haematoxylin and eosin. Liver sections showed normal architecture with distinct hepatic cells, sinusoidal spaces, and a central vein in all treatment groups and untreated; mild hepatocellular swelling is seen in all groups except the C5EOSEW5050ESA (200 mg/kg per day) group where no swelling is present. A: Untreated; B: Gemcitabine (10 mg/kg per 3 d); C: C5EOSEW5050ESA (200 mg/kg per day); D: C5EOSEW5050ESA (200 mg/kg per day) and gemcitabine (10 mg/kg per 3 d) combination; E: C5EOSEW5050ESA (400 mg/kg per day); F: C5EOSEW5050ESA (400 mg/kg per day) and gemcitabine (10 mg/kg per 3 d) combination.