Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer

doi:10.3748/wjg.v28.i32.4649

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2022; 28(32): 4649-4667
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4649

Table 2 The 20 downregulated genes that displayed the greatest changes in their expression in anoctamin 5-depleted NUGC4 cells

Gene symbol	Gene name	Gene ID	Fold change
CDK2	Cyclin-dependent kinase 2	TC1200007819.hg.1	-53.84
DTL	Denticleless E3 ubiquitin ligase homolog	TC0100011512.hg.1	-27.60
RABL3	RAB, member of RAS oncogene family like 3	TC0300012157.hg.1	-20.16
CKS1B	CDC28 protein kinase regulatory submit 1B	TC0100010100.hg.1	-19.34
LMNB1	Lamin B1	TC0500008544.hg.1	-19.18
IFRD2	Interferon-related developmental regulator 2	TC0300013981.hg.1	-18.61
PLK1	Polo like kinase 1	TC1600007235.hg.1	-17.89
GINS1	GINS complex subunit 1	TC2000007016.hg.1	-17.87
CDK6	Cyclin-dependent kinase 6	TC0700011785.hg.1	-17.08
XRCC2	X-ray repair cross complementing 2	TC0700013119.hg.1	-14.77
POGLUT3	Protein O-glucosyltransferase 3	TC1100012229.hg.1	-14.47
DSG2	Desmoglein 2	TC1800007014.hg.1	-14.37
NEMP1	Nuclear envelope integral membrane protein 1	TC1200010946.hg.1	-14.31
CBX5	Chromobox 5	TC1200010833.hg.1	-14.20
ANKRD52	Ankyrin repeat domain 52	TC1200010902.hg.1	-14.20
ITGB1	Integrin subunit beta 1	TC1000010265.hg.1	-14.16
H2BC14	H2B clustered histone 14	TC0600007377.hg.1	-13.25
SCAMP2	Secretory carrier membrane protein 2	TC1500010047.hg.1	-13.05
CMTM7	CKLF like MARVEL transmembrane domain containing 7	TC0300006968.hg.1	-13.02
GINS4	GINS complex subunit 4	TC0800007416.hg.1	-12.66

Citation: Fukami T, Shiozaki A, Kosuga T, Kudou M, Shimizu H, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Morinaga Y, Konishi E, Otsuji E. Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer. World J Gastroenterol 2022; 28(32): 4649-4667
URL: https://www.wjgnet.com/1007-9327/full/v28/i32/4649.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i32.4649