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Copyright ©The Author(s) 2022.
World J Gastroenterol. Aug 28, 2022; 28(32): 4527-4539
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4527
Table 1 Different microbial compositions in patients affected by pancreatic cancer
Anatomical district
Microbiota
Implications
Oral
Higher microbial biodiversityConfer higher risk of developing PanCa[17,19,20,23]
Porphyromonas gingivalis, Fusobacterium
Aggregatibacter actinomycetemcomitans
Streptococcus, Leptotrichia, Neisseria elongata
Granulicatella adiacensMore abundant in PanCa than control[23]
Fusobacterium, Rothia, Actinomyces
Corynebacterium, Atopobium
Peptostreptococcus, Catonella
Oribacterium, Filifactor
Campylobacter, Moraxella, Tannerella
Fungi:
Candida
Gut
BacteroidetesMore abundant in PanCa than control[27,28]
Prevotella, Hallella
Proteobacteria
Klebsiella, Enterobacter
Verrucomicrobia
Bifidobacterium pseudolongum
Veillonella
FirmicutesLess abundant in PanCa than control[27]
Coprococcus, Anaerostipes
Pancreas
ProteobacteriaMore abundant in PanCa than control[17,28,30-33]
Gammaproteobacteria
Pseudomonas, Acinetobacter, Enterobacter
Delftia, Klebsiella, Sphingomonas
Firmicutes
Enterococcus, Streptococcus, Staphylococcus
Fusobacteria
Fusobacterium species
Acinetobacteria
Bifidobacterium pseudolongum
Corynebacterium, Propionibacterium
LactobacillusLess abundant in PanCa than control[17,33]
FungiConfer higher risk of PanCa progression[31]
Malassezia