Copyright
©The Author(s) 2022.
World J Gastroenterol. Aug 28, 2022; 28(32): 4527-4539
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4527
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4527
Anatomical district | Microbiota | Implications |
Oral | ||
Higher microbial biodiversity | Confer higher risk of developing PanCa[17,19,20,23] | |
Porphyromonas gingivalis, Fusobacterium | ||
Aggregatibacter actinomycetemcomitans | ||
Streptococcus, Leptotrichia, Neisseria elongata | ||
Granulicatella adiacens | More abundant in PanCa than control[23] | |
Fusobacterium, Rothia, Actinomyces | ||
Corynebacterium, Atopobium | ||
Peptostreptococcus, Catonella | ||
Oribacterium, Filifactor | ||
Campylobacter, Moraxella, Tannerella | ||
Fungi: | ||
Candida | ||
Gut | ||
Bacteroidetes | More abundant in PanCa than control[27,28] | |
Prevotella, Hallella | ||
Proteobacteria | ||
Klebsiella, Enterobacter | ||
Verrucomicrobia | ||
Bifidobacterium pseudolongum | ||
Veillonella | ||
Firmicutes | Less abundant in PanCa than control[27] | |
Coprococcus, Anaerostipes | ||
Pancreas | ||
Proteobacteria | More abundant in PanCa than control[17,28,30-33] | |
Gammaproteobacteria | ||
Pseudomonas, Acinetobacter, Enterobacter | ||
Delftia, Klebsiella, Sphingomonas | ||
Firmicutes | ||
Enterococcus, Streptococcus, Staphylococcus | ||
Fusobacteria | ||
Fusobacterium species | ||
Acinetobacteria | ||
Bifidobacterium pseudolongum | ||
Corynebacterium, Propionibacterium | ||
Lactobacillus | Less abundant in PanCa than control[17,33] | |
Fungi | Confer higher risk of PanCa progression[31] | |
Malassezia |
- Citation: Bartolini I, Nannini G, Risaliti M, Matarazzo F, Moraldi L, Ringressi MN, Taddei A, Amedei A. Impact of microbiota-immunity axis in pancreatic cancer management. World J Gastroenterol 2022; 28(32): 4527-4539
- URL: https://www.wjgnet.com/1007-9327/full/v28/i32/4527.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i32.4527