Expanding beyond endoscopy: A review of non-invasive modalities in Barrett’s esophagus screening and surveillance

doi:10.3748/wjg.v28.i32.4516

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2022; 28(32): 4516-4526
Published online Aug 28, 2022. doi: 10.3748/wjg.v28.i32.4516

Table 1 Non-endoscopic methods for detection of Barrett’s esophagus

Device name	Application	Detection method	Company	FDA approved	Commercially available
Esophageal capsule endoscopy (ECE)	Swallowed	Direct visualization	Given imaging	Yes (First generation: 2004)	Three generations (SB1, SB2, SB3)
Tethered capsule endomicroscopy (OTC-TCE)	Swallowed	Direct visualization	N/A	No	No
Cytosponge	Swallowed	Cell collection	Medtronic	Yes (2018)	Yes
Esophacap	Swallowed	Cell collection	PAVmed (previously CapNostics)	Yes (2021)	No
EsoCheck	Swallowed	Cell collection	PAVmed (Lucid Diagnostics)	Yes (2019)	Yes
Circulatory microRNAs	Blood sample	miRNA collection	N/A	No	No
Volatile organic compounds (VOC)	Breath sample	VOC collection	Aeonose (Netherlands)	No	No

Citation: Shahsavari D, Kudaravalli P, Yap JEL, Vega KJ. Expanding beyond endoscopy: A review of non-invasive modalities in Barrett’s esophagus screening and surveillance. World J Gastroenterol 2022; 28(32): 4516-4526
URL: https://www.wjgnet.com/1007-9327/full/v28/i32/4516.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i32.4516