Observational Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Aug 21, 2022; 28(31): 4417-4430
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4417
Table 4 Association of risk factors with acute-on-chronic liver failure development during hospitalization using logistic regression in univariate and multivariate analysis

OR
95%CI
P value
Univariable logistic regression
Demographic data
Age0.960.21-6.180.96
Male2.890.83-9.170.08
Etiology0.900.43-1.700.76
Acute decompensation events
Overt ascites0.920.3-3.140.89
Gastrointestinal bleeding0.740.11-2.90.7
Bacterial infection2.220.69-6.950.17
Hepatic encephalopathy3.60.51-15.950.13
Laboratory data
Total bilirubin1.681.14-2.610.012
International normalized ratio6.531.9-28.550.006
Creatinine0.850.51-1.870.6
Blood urea nitrogen1.520.84-2.630.12
Albumin0.440.07-3.190.4
ALT1.250.85-1.820.24
AST1.140.73-1.750.55
White blood cells0.880.45-1.750.72
Hemoglobin0.390.11-1.50.16
K1.530.13-18.280.74
Sodium00-288.550.29
Neutrophil-lymphocyte ratio1.370.84-2.230.21
ALP1.150.59-2.270.7
GGT0.860.54-1.340.52
Multivariable logistic regression
Male3.240.84-11.630.07
TB1.561.03-2.470.046
INR4.311.15-21.700.048

  • Citation: Shen ZX, Wu DD, Xia J, Wang XB, Zheng X, Huang Y, Li BL, Meng ZJ, Gao YH, Qian ZP, Liu F, Lu XB, Shang J, Yan HD, Zheng YB, Gu WY, Zhang Y, Wei JY, Tan WT, Hou YX, Zhang Q, Xiong Y, Zou CC, Chen J, Huang ZB, Jiang XH, Luo S, Chen YY, Gao N, Liu CY, Yuan W, Mei X, Li J, Li T, Zhou XY, Deng GH, Chen JJ, Ma X, Li H. Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China. World J Gastroenterol 2022; 28(31): 4417-4430
  • URL: https://www.wjgnet.com/1007-9327/full/v28/i31/4417.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v28.i31.4417