Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China

Table 3 The impact of etiology on liver transplantation-free mortality in acute-on-chronic liver failure patients with cirrhosis and acute decompensation (primary biliary cirrhosis as a reference)

	n	Num of death (percentage)	Unadjusted OR (95%CI), P value	Adjusted I1, OR (95%CI), P value	Adjusted II2, OR (95%CI), P value
28-d LT-free mortality
PBC	111	7 (6.3)	1.0	1.0	1.0
AIH	67	4 (6.0)	0.94 (0.24-3.25), 0.93	0.94 (0.24-3.24), 0.92	1.26 (0.3-4.85), 0.74
PBC/AIH	28	5 (17.9)	3.23 (0.89-11.05), 0.06	3.43 (0.93-11.93), 0.05	2.61 (0.63-10.21), 0.17
Others	19	2 (10.5)	1.75 (0.25-7.99), 0.51	1.75 (0.24-8.13), 0.51	1.46 (0.17-8.28), 0.70
90-d LT-free mortality
PBC	103	19 (18.4)	1.0	1.0	1.0
AIH	64	8 (12.5)	0.63 (0.25-1.50), 0.31	0.64 (0.25-1.53), 0.33	0.74 (0.27-1.88), 0.54
PBC/AIH	26	7 (26.9)	1.63 (0.57-4.31), 0.34	1.70 (0.59-4.56), 0.30	1.18 (0.36-3.56), 0.77
Others	18	2 (11.1)	0.55 (0.08-2.17), 0.45	0.51 (0.08-2.02), 0.40	0.44 (0.05-2.08), 0.36
365-d LT-free mortality
PBC	97	30 (30.9)	1.0	1.0	1.0
AIH	63	16 (25.4)	0.76 (0.37-1.54), 0.45	0.76 (0.36-1.53), 0.44	0.81 (0.38-1.68), 0.58
PBC/AIH	23	11 (47.8)	2.05 (0.9-5.20), 0.13	2.06 (0.81-5.24), 0.13	1.72 (0.63-4.61), 0.28
Others	18	5 (27.8)	0.86 (0.26-2.51), 0.79	0.89 (0.26-2.62), 0.84	0.82 (0.24-2.49), 0.74

¹Adjusted age, gender.

²Adjusted age, gender, hepatic encephalopathy, ascites, infection and gastrointestinal bleeding.

OR: Odds ratio; CI: Confidence interval; PBC: Primary biliary cirrhosis; AIH: Autoimmune hepatitis; PBC/AIH: Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome; LT: Liver transplantation.