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©The Author(s) 2022.
World J Gastroenterol. Aug 21, 2022; 28(31): 4310-4327
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4310
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4310
Table 2 Characterization of hereditary risk group: Germline mutations and personal history of cancer, n = 20
| Lynch syndrome, n = 17 (85.0%) | Peutz-Jeghers syndrome, n = 1 (5.0%) | FPC, n = 2 (10.0%) | |
| Germline mutation(s) | |||
| MLH1 | 7 (41.2) | - | - |
| MSH2 | 6 (35.3) | - | - |
| MLH1 + MSH2 | 1 (5.9) | - | - |
| MSH2 + MSH6 | 2 (11.7) | - | - |
| MSH6 | 1 (5.9) | - | - |
| STK11 | - | 1 (100.0) | - |
| Not identified | - | 2 (100.0) | |
| Personal history of cancer | |||
| No | 11 (64.7) | 1 (100.0) | 2 (100.0) |
| Yes | 6 (35.3) | 0 (0.0) | 0 (0.0) |
| Type of cancer | |||
| Colon and rectum | 5 (83.3%) | - | - |
| Endometrium | 1 (16.7) | - | - |
- Citation: Moutinho-Ribeiro P, Batista IA, Quintas ST, Adem B, Silva M, Morais R, Peixoto A, Coelho R, Costa-Moreira P, Medas R, Lopes S, Vilas-Boas F, Baptista M, Dias-Silva D, Esteves AL, Martins F, Lopes J, Barroca H, Carneiro F, Macedo G, Melo SA. Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities. World J Gastroenterol 2022; 28(31): 4310-4327
- URL: https://www.wjgnet.com/1007-9327/full/v28/i31/4310.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i31.4310