Involvement of nitrergic neurons in colonic motility in a rat model of ulcerative colitis

Figure 5 Relative nitric oxide synthase protein expression in the colonic myenteric plexus. A: Western blot analysis of expression of nitric oxide synthase (NOS) in the colonic myenteric plexus (MP) of rats in the four groups; B: Comparison of the relative expression of NOS protein in the colonic MP of rats in the four groups showing statistically significant differences between EG groups and CG group (^bP < 0.0001), and between EG2-3 groups and EG1 group (^aP < 0.05). CG: Control group; UC: Ulcerative colitis; NOS: Nitric oxide synthase; L-NMMA: NG-monomethyl-L-arginine monoacetate; EG1: UC group; EG2: UC + NOS agonist TP508TFA group; EG3: UC + NOS inhibitor L-NMMA group; NOS: Nitric oxide synthase; MP: Myenteric plexus.