Involvement of nitrergic neurons in colonic motility in a rat model of ulcerative colitis

Figure 3 Histological evaluation. A: HE stained rat colon tissues. a: CG; b: EG1; c: EG2; d: EG3. Scale bar = 100 μm; B: Comparison of colonic histological index scores showing statistically significant differences between EG groups and CG group (^bP < 0.0001) and between EG2-3 groups and EG1 group (^aP < 0.05). CG: Control group; UC: Ulcerative colitis; NOS: Nitric oxide synthase; L-NMMA: NG-monomethyl-L-arginine monoacetate; EG1: UC group; EG2: UC + NOS agonist TP508TFA group; EG3: UC + NOS inhibitor L-NMMA group; HI: Histological index.