Involvement of nitrergic neurons in colonic motility in a rat model of ulcerative colitis

Figure 2 Colon length in each group and results of the open field test. A: Colon length of rats in the four groups; B: Comparison of colon length in CG (19.71 ± 0.11 cm), EG1 (16.59 ± 0.35 cm), EG2 (17.80 ± 0.19 cm), and EG3 (15.11 ± 0.44 cm) groups. There were statistically significant differences between EG groups and CG group (^bP < 0.0001), and between EG2-3 groups and EG1 group (^aP < 0.05); C: Movement trajectories of rats. a: CG; b: EG1; c: EG2; d: EG3; D: Results of the open field test. There were statistically significant differences between EG groups and CG group (^bP < 0.0001), and between EG2-3 groups and EG1 group (^aP < 0.05). CG: Control group; UC: Ulcerative colitis; NOS: Nitric oxide synthase; L-NMMA: NG-monomethyl-L-arginine monoacetate; EG1: UC group; EG2: UC + NOS agonist TP508TFA group; EG3: UC + NOS inhibitor L-NMMA group.