High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1

doi:10.3748/wjg.v28.i29.3838

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2022; 28(29): 3838-3853
Published online Aug 7, 2022. doi: 10.3748/wjg.v28.i29.3838

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Figure 7 Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 encapsulated by mesenteric adipose tissue-derived exosomes targets the colon to aggravate colitis via the microRNA-15a-5p/activating transcription factor 6 axis in response to endoplasmic reticulum stress. ATF-6: Activating transcription factor 6; LnRNA: Long non-coding RNA; IL: Interleukin; TNF-α: Tumor necrosis factor-α; ER: Endoplasmic reticulum; MAT-Exos: Mesenteric adipose tissue derived exosomes; MALAT1: Metastasis-associated lung adenocarcinoma transcript 1.

Citation: Chen D, Lu MM, Wang JH, Ren Y, Xu LL, Cheng WX, Wang SS, Li XL, Cheng XF, Gao JG, Kalyani FS, Jin X. High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1. World J Gastroenterol 2022; 28(29): 3838-3853
URL: https://www.wjgnet.com/1007-9327/full/v28/i29/3838.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i29.3838