High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1

Figure 3 Mesenteric adipose tissue derived exosomes from high-fat diet-fed mice increase the expression of long noncoding RNAs metastasis-associated lung adenocarcinoma transcript 1 in colon. A: Expression of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in mesenteric adipose tissue derived exosomes (MAT-Exos) in each group; B: Expression of MALAT1 in mesenteric adipose tissue in each group; C: Expression of MALAT1 in colon in each group; D: Expression of MALAT1 in colon of normal mice after treated with MAT-Exos extracted from higt-fat diet mice or normal diet mice. MALAT1: Metastasis-associated lung adenocarcinoma transcript 1; TNBS: 2,4,6-trinitrobe-nzenesulfonic acid; HFD: High-fat diet; ND: Normal diet. ^bP < 0.01.