High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1

Figure 1 High-fat diet aggravated colitis. A: Experimental grouping process; B: Colon length of mice in each group; C: Disease activity index of mice in each group; D: Body weight change trend of mice in each group; E: Hematoxylin and eosin staining images of colon tissue; F: Histological damage score of colon tissue; G: Expression of tumor necrosis factor-α in colon tissue by enzyme linked immunosorbent assay (ELISA); H: Expression of interleukin-1β in colon tissue by ELISA; I: Expression of interleukin-6 (IL-6) in colon tissue by ELISA. DAI: Disease activity index; TNBS: 2,4,6-trinitrobe-nzenesulfonic acid; HFD: High-fat diet; ND: Normal diet; TNF-α: Tumor necrosis factor-α; IL-1β: Interleukin-1β. ^aP < 0.05, ^bP < 0.01.