Incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis: A retrospective single-center study

Table 4 Comparisons of clinical characteristics and laboratory parameters with different treatment between intravenous insulin and hemoperfusion before and after propensity score matching

Characteristic	Entire cohort		P value	PSM		P value
	INS group (n = 84)	HP Group (n = 32)		INS group (n = 26)	HP group (n = 26)
Sex, n (%)			0.626			0.184
Male	51 (60.7)	21 (65.6)		20 (76.9)	16 (61.5)
Female	33 (39.3)	11 (34.4)		6 (23.1)	10 (38.5)
Age, yr	39.99 ± 10.36	36.44 ± 11.60	0.965	36.81 ± 10.79	36.42 ± 10.10	0.895
Grades of severity, n (%)			0.002			0.755a
MAP	14 (16.7)	1 (3.1)		1 (3.8)	1 (3.8)
MSAP	69 (82.1)	26 (81.3)		25 (96.2)	25 (96.2)
SAP	1 (1.2)	5 (15.6)		0 (0.0)	0 (0.0)
Improved Marshall score	0.00 (0.00, 1.00)	1.00 (1.00, 2.00)	< 0.001	0.00 (0.00, 1.00)	1.00 (0.00, 1.00)	0.186a
MCTSI score	4.67 ± 1.59	5.75 ± 0.84	< 0.001	5.15 ± 1.29	5.62 ± 0.80	0.127a
Baseline TG, mg/dL	2493.20 ± 1958.06	3443.88 ± 1676.31	0.037	3484.64 ± 2275.248	3264.91 ± 2375.37	0.734a
Treated TG within 48 h, mg/dL	946.25 ± 769.05	1145.60 ± 699.05	0.205	1108.39 ± 856.76	1040.16 ± 686.65	0.753
Clearance rate of TG within 48 h, %	47.65 ± 34.64	63.91 ± 23.32	0.005	57.24 ± 33.70	56.38 ± 33.61	0.927a
CRP, mg/L	184.75 ± 99.84	198.43 ± 94.00	0.552	214.612 ± 119.22	198.28 ± 97.09	0.629
Albumin, g/L	34.05 ± 4.81	32.50 ± 6.39	0.219	34.56 ± 5.03	32.53 ± 6.58	0.218
TBIL, mmol/L	17.80 ± 8.96	19.83 ± 13.61	0.439	18.70 ± 9.38	20.87 ± 14.41	0.523
ALT, U/L	24.55 ± 17.77	23.15 ± 18.15	0.705	24.58 ± 16.69	21.81 ± 16.47	0.550
AST, U/L	25.70 ± 14.23	30.85 ± 26.87	0.187	24.84 ± 12.40	32.10 ± 29.44	0.252
Total cholesterol, mmol/L	8.38 ± 3.89	8.93 ± 4.37	0.511	9.84 ± 4.91	8.52 ± 4.58	0.318
Glucose, mmol/L	11.08 ± 3.65	10.83 ± 3.42	0.739	11.71 ± 2.74	10.07 ± 3.22	0.057
Urea nitrogen, mmol/L	4.02 ± 1.86	3.83 ± 2.27	0.652	3.54 ± 1.76	3.34 ± 1.94	0.688
Creatinine, mmol/L	63.73 ± 18.23	67.72 ± 24.01	0.338	65.00 ± 12.33	67.00 ± 23.36	0.702
Calcium, mmol/L	1.98 ± 0.25	1.90 ± 0.28	0.100	2.03 ± 0.23	1.89 ± 0.31	0.063
WBC, × 109/L	11.79 ± 4.20	12.33 ± 4.37	0.541	12.40 ± 4.00	12.51 ± 4.44	0.920
PLT, × 109/L	205.39 ± 68.44	204.34 ± 65.98	0.941	201.66 ± 59.77	197.38 ± 57.91	0.795
Hb, g/L	137.48 ± 23.67	138.12 ± 27.60	0.902	143.44 ± 19.50	135.38 ± 27.50	0.230
Length of stay, d	11.88 ± 6.37	11.93 ± 6.01	0.965	13.04 ± 7.92	12.35 ± 6.40	0.730
Death, n (%)	0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)

^aP value changed after propensity score matching.

PSM: Propensity score matching; INS: Intravenous insulin; HP: Hemoperfusion; MAP: Mild acute pancreatitis; MSAP: Moderately severe acute pancreatitis; SAP: Severe acute pancreatitis; MCTSI: Modified computed tomography severity index; TG: Triglyceride; CRP: C-reactive protein; TBIL: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate transaminase; WBC: White blood cell; PLT: Blood platelet; Hb: Hemoglobin.