Family-based Helicobacter pylori infection status and transmission pattern in central China, and its clinical implications for related disease prevention

Table 4 Serum gastrin-17, pepsinogen I, pepsinogen II and pepsinogen I/II ratio levels in Helicobacter pylori-infected population

	H. pylori+	Type I H. pylori	Type II H. pylori	H. pylori-
G-17 (pmol/L)	8.95 ± 14.53	9.87 ± 15.60	5.62 ± 9.10c	4.90 ± 9.21a,d
PGI (μg/L)	117.90 ± 55.99	123.12 ± 57.11	99.10 ± 47.45	91.13 ± 38.29a,b,d
PGII (μg/L)	12.66 ± 10.41	13.83 ± 11.07	8.43 ± 5.91c	7.39 ± 6.82a,d
PGR	12.16 ± 6.39	11.64 ± 6.40	14.05 ± 6.04c	15.58 ± 7.97a,d

^aP < 0.05 when type I Helicobacter pylori (H. pylori)-infected groups were compared with H. pylori-negative groups.

^bP < 0.05 when type II H. pylori-infected groups were compared with H. pylori-negative groups.

^cP < 0.05 when type I H. pylori-infected groups were compared with type II H. pylori-infected groups.

^dP < 0.05 when H. pylori-infected groups were compared with H. pylori-negative groups.

Data are presented as mean ± SD. G-17: Gastrin-17; PG: Pepsinogen; PGR: PG I/II ratio; Type I H. pylori: H. pylori infection with type I strains; Type II H. pylori: H. pylori infection with type II strains; H. pylori: Helicobacter pylori; H. pylori+: H. pylori-positive; H. pylori-: H. pylori-negative.