Family-based Helicobacter pylori infection status and transmission pattern in central China, and its clinical implications for related disease prevention

Table 1 Demography information and Helicobacter pylori infection status of 772 subjects

Variables items, n	H. pylori positive			H. pylori negative, n	Infection rate (%)	P value
	Sub total, n	Type I, n	Type II, n
Total (772)	419	328	91	353	54.27
Gender
Male (330)	173	130	43	157	52.42
Female (442)	246	198	48	196	55.66	0.373
Age (yr) (mean ± SD)1
Total (45.36 ± 19.38)	49.38 ± 16.92	49.59 ± 17.04	48.65 ± 16.47	40.58 ± 20.97		0.000a
Male (44.56 ± 20.19)	49.62 ± 18.06	49.21 ± 18.53	50.86 ± 16.50	38.98 ± 20.93
Female (45.95 ± 18.74)	49.22 ± 16.06	49.83 ± 15.97	46.67 ± 16.20	41.86 ± 20.92		0.240b
Family annual income2 (10000 RMB)
< 10 (287)	171	142	29	116	59.58
10-20 (209)	119	86	33	90	56.94	0.555c
20-30 (84)	47	36	11	37	55.95	0.552c
> 30 (59)	34	27	7	25	57.63	0.781c
Unknown (47)	28	20	8	19	59.57
Cigarette smoking2
Yes (158)	91	64	27	67	57.59
No (520)	302	242	60	218	58.08	0.914
Unknown (8)	6	5	1	2	75.00
Alcohol drinking2
Yes (149)	86	64	22	63	57.72
No (511)	297	233	64	214	58.12	0.930
Unknown (26)	16	14	2	10	61.54
Gastrointestinal symptoms2
Yes (311)	183	145	38	128	58.84
No (339)	193	148	45	146	56.93	0.622
Unknown (36)	23	18	5	13	63.89
Dining location2
Home (472)	276	215	61	196	58.47
Restaurant (186)	106	83	23	80	56.99	0.728
Unknown (28)	17	13	4	11	60.71
Family history of stomach disease3
Yes (167)	92	65	27	75	55.09
No (430)	256	205	51	174	59.53	0.323
Unknown (89)	51	41	10	38	57.30
Family history of gastric cancer3
Yes (41)	23	20	3	18	56.10
No (576)	335	260	75	241	58.16	0.796
Unknown (69)	41	31	10	28	59.42
Education level2
Senior and below (286)	180	142	38	106	62.94
University or above (376)	199	155	44	177	52.93	0.010a
Unknown (24)	20	14	6	4	83.33

^aP < 0.05, when Helicobacter pylori (H. pylori)-positive groups were compared with H. pylori-negative groups.

^bP > 0.05, when male H. pylori-positive groups were compared with female H. pylori-positive groups.

^cP > 0.05, when H. pylori infection rate in the annual income < 100000 RMB group was compared with other income groups.

¹Data are presented as the mean ± SD.

²Data only included adults, and children and adolescents age ≤ 18 yr were not included.

³Data only included history of gastric disease or gastric cancer in families across three consecutive generations.

H. pylori: Helicobacter pylori.