Gastric mucosal precancerous lesions in Helicobacter pylori-infected pediatric patients in central China: A single-center, retrospective investigation

Table 1 Demographic and clinical data of patients

Variables	Total	H. pylori+	H. pylori-	P value
Patients, n	1015	854	161
Age in year, median (IQR)	11 (9-13)	11 (9-13)	9 (6-12)	< 0.001a
Sex, n (%)
Female	411 (40.49)	346 (40.52)	65 (40.37)
Male	604 (59.51)	508 (59.48)	96 (59.63)	0.973
Endoscopic pattern, n (%)
Esophagitis	28 (2.76)	23 (2.69)	5 (3.11)	0.975
Superficial gastritis	331 (32.61)	255 (29.86)	76 (47.20)	< 0.001b
Superficial gastritis with erosion	236 (23.25)	200 (23.42)	36 (22.36)	0.77
Superficial gastritis with bile reflux	295 (29.06)	251 (29.39)	44 (27.33)	0.597
Antral nodularity	135 (13.30)	131 (15.34)	4 (2.48)	< 0.001b
Peptic ulcer	90 (8.87)	80 (9.37)	10 (6.21)	0.196
Atrophic gastritis	18 (1.77)	17 (1.99)	1 (0.62)	0.378
Clinical diagnosis, n (%)
Esophagitis	28 (2.76)	23 (2.69)	5 (3.11)	0.975
Non atrophic gastritis	997 (98.23)	837 (98.01)	160 (99.38)	0.378
Atrophic gastritis	18 (1.77)	17 (1.99)	1 (0.62)	0.378
Gastric ulcer	18 (1.77)	16 (1.87)	2 (1.24)	0.817
Duodenal ulcer	72 (7.09)	64 (7.49)	8 (4.97)	0.252

^aP < 0.05: Median age was compared between Helicobacter pylori (H. pylori)-positive and -negative groups.

^bP < 0.05: When compared between H. pylori–positive and –negative within each disease group.

IQR: Interquartile range; H. pylori: Helicobacter pylori.