Contrast-enhanced ultrasound Liver Imaging Reporting and Data System: Lights and shadows in hepatocellular carcinoma and cholangiocellular carcinoma diagnosis

Figure 2 Examples of different contrast-enhanced ultrasound Liver Imaging Reporting and Data System classes. A: Contrast-enhanced ultrasound (CEUS) LR-M. Notice rim arterial phase hyperenhancement and early washout, before 60 s; B: CEUS LR-5. Notice homogeneous arterial phase hyperenhancement, isoenhancement in portal phase, and mild washout in the late phase; C: CEUS LR-4. Notice homogeneous arterial phase hyperenhancement and isoenhancement in both portal and late phases; D: CEUS LR-3 iso-iso. Notice isoenhancement in all phases; E: CEUS LR-3 hypo-hypo. Notice hypoenhancement in all phases. The arrows show the target lesion.