Involvement of Met receptor pathway in aggressive behavior of colorectal cancer cells induced by parathyroid hormone-related peptide

Figure 9 Relation of Met and parathyroid hormone receptor type 1 staining intensity with tumor histological differentiation. A: Quantification of the immunostaining by optical density analysis using the FIJI plug-in from the Image J program; B: Representative images (200 ×) obtained by hematoxylin-eosin staining and by the immunohistochemistry technique performed for Met and PTHR1 for normal colorectal tissue and colorectal cancer tissue, with histological grades G1, G2, and G3. Scale bar: 10 μM. H-E: Hematoxylin-eosin staining; Met: Receptor tyrosine kinase Met; NT: Normal tissue; PTHR1: Parathyroid hormone receptor type 1.