Involvement of Met receptor pathway in aggressive behavior of colorectal cancer cells induced by parathyroid hormone-related peptide

Figure 6 Analysis of the aspect ratio (major/minor axis) of HCT116 cells, obtained using the Image J-NIH program. The table shows values of parameters associated to cell morphology: Area; perimeter; round; major axis; minor axis; and aspect radio, relation between major axis and minor axis (AR). Graph bars show the AR for each condition. The increase of the degree of cell elongation at 24 h of exposure to parathyroid hormone-related peptide was significantly reversed in the presence of the Met inhibitor. DMSO: Dimethylsulfoxide; PTHrP: Parathyroid hormone-related peptide; SU: SU11274. ^bP < 0.01.