Retrospective Cohort Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Jul 14, 2022; 28(26): 3218-3231
Published online Jul 14, 2022. doi: 10.3748/wjg.v28.i26.3218
Table 3 Post transplant outcomes
Total (n = 111)BMI after ascites correction
P value
Overweight or obese (n = 82)
Underweight or normal (n = 29)
Biliary stricture, n (%)22 (19.8)16 (19.5)6 (20.7)0.97
Biliary leak, n (%)10 (9)7 (8.5)3 (10.3)1.0
Hepatic artery thrombosis, n (%)2 (1.8)0 (0)2 (6.9)0.07
90-d re-hospitalization (n = 103), n (%)23 (22.3)17 (22.6)6 (21.4)0.89
Recurrent NAFLD, n (%)57 (51.4)44 (53.7)13 (44.8)0.59
Time to recurrent NAFLD, median (range) days568 (13–2135)489 (13–1821)757 (80–2135)0.21
Recurrent NASH, n (%)7 (6.3)5 (6.1)2 (6.9)1.0
Time to recurrent NASH, median (range) days812 (363–1119)802 (363–1119)957.5 (812–1103)0.28
BMI at 1 yr (n = 83), median (range) kg/m230.3 (19.2–44.0)31.7 (23.2–44.0)26.1 (19.2–34.2)< 0.001c
BMI at 5 yr (n = 17), median (range) kg/m233.9 (20.3–47.9)35.1 (26.6 – 47.9)27.0 (20.3–31.5)0.004b
Creatinine at 1 yr (n = 70), median (range) μmol/L114.0 (54.0–279.0)117.5 (63.0–279.0)106.0 (54.0–178.0)0.21
Creatinine at 5 yr (n = 19), median (range) μmol/L143.0 (67.0-257.0)153.5 (78.0–257.0)111.0 (67.0–127.0)0.019a
Diabetes at 1 yr (n = 82), n (%)36 (43.9)27 (45.8)9 (39.1)0.59
Diabetes at 5 yr (n = 20), n (%)10 (50)8 (53.3)2 (40)0.72
Hypertension at 1 yr (n = 83), n (%)44 (53)33 (55)11 (47.8)0.56
Hypertension at 5 yr (n = 20), n (%)12 (60)10 (66.7)2 (40)0.35
Cardiovascular events post LT, n (%)22 (19.8)14 (17)8 (27.6)0.45
Fibroscan Elastography (n = 48), median (range) kPa6.4 (2.3–21.8)6.8 (3.5–21.8)4.8 (2.3–14.5)0.011a
Fibroscan CAP (n = 48), median (range) dB/m286.5 (181.0–400.0)298.0 (198.0–400.0)283.5 (181.0–400.0)0.26
Graft loss within 90 d post LT, n (%)5 (4.5)1 (1.2)4 (13.8)0.032a
Graft survival post LT 1 yr (n = 101), n (%)94 (93.1)72 (98.6)22 (78.6)0.002b
Graft survival post LT 3 yr (n = 72), n (%)65 (90.3)48 (96)17 (77.3)0.025a
Graft survival post LT 5 yr (n = 32), n (%)22 (68.8)17 (85)5 (41.7)0.018a
Deaths post LT, n (%)7 (6.3)2 (2.4)5 (17.2)0.029a
Time to death post LT (n = 7), median (range) days224 (13–1176)192.5 (20–365)224 (13–1176)0.42
Death within 90 d post-LT, n (%)2 (1.8)1 (1.2)1 (3.4)0.38
Patient survival at 1 yr (n = 108), n (%)104 (96.3)78 (98.7)26 (89.7)0.06
Patient survival at 3 yr (n = 97), n (%)66 (91.7)48 (96)18 (81.8)0.07
Patient survival at 5 yr (n = 32), n (%)25 (78.1)18 (90)7 (58.3)0.07
aP < 0.05.
bP < 0.01.
cP < 0.001.
BMI: Body mass index; CAP: Controlled attenuation parameter; LT: Liver transplant; NAFLD: Non-alcoholic fatty liver disease; NASH: Non-alcoholic steatohepatitis.