Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization

Figure 5 Signaling pathway analysis by Western blot assay. A: Western blot results indicate that the expression level of p-JAK, p-STAT3, and receptor-related orphan receptor (ROR) were significantly increased in the CD4+ T cell + CGS21680 group and decreased in CD4+ T cell + Sch58261 group; B: The mRNA expression level of p-JAK, p-STAT3, and ROR between the different groups. ^aP < 0.05. A2AR: Adenosine 2A receptor; PI-IBS: Post-infectious irritable bowel syndrome; NS: Not significant.