Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization

Figure 4 Functional evaluation of CD4+ T cells in vitro. A: CCK-8 assay indicated that CD4+ T cells from post-infectious irritable bowel syndrome mice showed increased proliferation ability; B: Apoptosis analysis of CD4+ T cells between the three groups; C: ATP expression in CD4+ T cells between the three groups; D: Expression level of IFN-γ and IL-17 in the three groups. ^aP < 0.05. A2AR: Adenosine 2A receptor; PI-IBS: Post-infectious irritable bowel syndrome; NS: Not significant.