Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization

doi:10.3748/wjg.v28.i25.2955

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Jul 7, 2022 (publication date) through Jul 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2022; 28(25): 2955-2967
Published online Jul 7, 2022. doi: 10.3748/wjg.v28.i25.2955

Table 4 The effect of adenosine 2A receptor on intestinal mobility in the post-infectious irritable bowel syndrome mouse

Group	Time to first black stool (min)	Bristol stool grade
Control (n = 6)	105.39 ± 15.16	1.01 ± 0.12
PI-IBS (n = 6)	69.45 ± 8.72^a	2.54 ± 0.48^a
IBS + Sch58261 (n = 6)	94.70 ± 14.56^c	1.29 ± 0.35^c
IBS + CGS21680 (n = 6)	78.91 ± 9.74	3.11 ± 0.54

^aP < 0.05 vs control group.

^cP < 0.05 vs post-infectious irritable bowel syndrome group. PI-IBS: Post-infectious irritable bowel syndrome.

Citation: Dong LW, Ma ZC, Fu J, Huang BL, Liu FJ, Sun D, Lan C. Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization . World J Gastroenterol 2022; 28(25): 2955-2967
URL: https://www.wjgnet.com/1007-9327/full/v28/i25/2955.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i25.2955