Fecal gene detection based on next generation sequencing for colorectal cancer diagnosis

Table 7 Comparison of pathogenic mutation sites in preoperative stools vs benign control group

Gene	Positive rate of pathogenic gene mutation sites		χ2	P value
	Preoperative feces	Benign control group
TP53	37.04% (10/27)	0	7.328	0.007
APC	11.11% (3/27)	0	0.878	0.349
KRAS	25.93% (7/27)	0	4.219	0.040
PIK3CA	3.70% (1/27)	0	Fisher exact test	1
FBXW7	3.70% (1/27)	0	Fisher exact test	1
GNAS	3.70% (1/27)	0	Fisher exact test	1
PTEN	3.70% (1/27)	0	Fisher exact test	1
ABL1	3.70% (1/27)	0	Fisher exact test	1
PDGFRA	3.70% (1/27)	0	Fisher exact test	1

Positive rate of pathogenic gene mutation site: The number of people with mutations corresponding to the pathogenic mutation sites of any gene/total number of samples.