Endoscopic classification and pathological features of primary intestinal lymphangiectasia

Table 1 Demography, clinical profile and laboratory examination of patients with primary intestinal lymphangiectasia

Clinical features	Total (n = 123)	Type				P value
		Nodular type (n = 17)	Granular type (n = 74)	Vesicular type (n = 5)	Edematous type (n = 27)
Demographic characteristics, mean ± SD (age range)/n (%)
Age of diagnosis (yr)	22.8 ± 19.2	10.2 ± 7.6	23.7 ± 20.6	25.2 ± 15.7	27.7 ± 18.3	< 0.001
Age of onset (yr)	17.0 ± 17.4 (0, 68)	3.7 ± 6.9 (0, 22)	17.9 ± 18.0 (0, 68)	22.2 ± 15.1 (3, 44)	21.7 ± 17.4 (0, 66)	< 0.001
Male	61 (49.6)	7 (41.2)	35 (47.3)	2 (40.0)	17 (63.0)	0.408
Clinical characteristics, n (%)
Diarrhea	72 (58.5)	12 (70.6)	47 (63.5)	3 (60.0)	10 (37.0)	0.074
Edema	96 (78.0)	13 (76.5)	59 (79.7)	2 (40.0)	22 (81.5)	0.238
Abdominal distension	28 (22.8)	6 (35.3)	15 (20.3)	1 (20.0)	6 (22.2)	0.567
Abdominal pain	10 (8.1)	0 (0)	7 (9.5)	0 (0)	3 (11.1)	0.603
Nausea and vomiting	8 (6.5)	0 (0)	8 (10.8)	0 (0)	0 (0)	0.145
Gastrointestinal bleeding	4 (3.3)	0 (0)	2 (2.7)	0 (0)	2 (7.4)	0.423
Fever	2 (1.6)	0 (0)	1 (1.4)	0 (0)	1 (3.7)	0.640
Laboratory examination, mean ± SD
LY	1.2 ± 0.9	1.0 ± 0.5	1.2 ± 1.1	0.3 ± 0.1	1.4 ± 0.9	< 0.001
HGB (g/L) (110-150)	129.9 ± 23.5	137.4±17.9	127.9 ± 24.5	116.4 ± 13.3	133.1 ± 24.3	0.221
TP (g/L) (60-80)	41.2 ± 9.0	39.9 ± 6.7	40.4 ± 8.7	39.9 ± 7.1	44.4 ± 10.8	0.218
Alb (g/L) (35-55)	25.4 ± 7.2	24.3 ± 5.9	25.5 ± 6.7	26.5 ± 5.7	25.6 ± 9.4	0.911
Glb (g/L) (20-30)	15.8 ± 4.3	15.3 ± 4.4	15.0 ± 3.2	13.4 ± 3.0	18.8 ± 5.5	0.024
IgG (g/L) (7-16)	3.91 ± 2.30	3.35 ± 1.48	3.73 ± 2.12	2.26 ± 0.43	5.01 ± 2.90	< 0.001
Ca (mmol/l) (2.1-2.75)	1.93 ± 0.28	1.90 ± 0.18	1.91 ± 0.31	1.86 ± 0.09	1.99 ± 0.26	0.556

Alb: Albumin; Ca: Calcium; Glb: Globulin; HGB: Hemoglobin; IgG: Immunoglobulin G; LY: Lymphocyte count; TP: Total protein.