Differentiating malignant and benign focal liver lesions in children using CEUS LI-RADS combined with serum alpha-fetoprotein

Table 6 Comparison of different criteria on indicators of diagnostic performance

P value	Sensitivity	Specificity	Accuracy	AUC
Criterion I vs criterion II	< 0.017	< 0.0001	< 0.017	> 0.017
Criterion I vs criterion III	-	< 0.0001	< 0.0001	< 0.0001
Criterion II vs criterion III	< 0.017	> 0.017	> 0.05	> 0.05

Criterion I considered LR-4, LR-5, or LR-M lesions as malignancies; criterion II regarded LR-4, LR-5 or LR-M lesions with simultaneously elevated alpha-fetoprotein (AFP, ≥ 20 ng/mL) as malignancies; criterion III took LR-4 lesions with elevated AFP or LR-5 or LR-M lesions as malignancies. AUC: Area under the curve.