Long noncoding RNA TNFRSF10A-AS1 promotes colorectal cancer through upregulation of HuR

Figure 6 TNFRSF10A-AS1 promotes the growth of colorectal cancer in vivo. A and B: Tumor volume and weight were significantly decreased in the TNFRSF10A-AS1 knockdown group but markedly increased in the TNFRSF10A-AS1 overexpression group; C-E: TNFRSF10A-AS1 enhanced cell proliferation (as assessed by Ki67 staining) and increased HuR expression (as assessed by HuR staining, quantitative real-time polymerase chain reaction and Western blot) in xenograft tumor tissues; F: HuR was upregulated in colorectal cancer patient tumor tissues compared to matched nontumor tissues by Western blot analysis.