Long noncoding RNA TNFRSF10A-AS1 promotes colorectal cancer through upregulation of HuR

Figure 4 miR-3121-3p suppresses colon cancer cell proliferation, migration and invasion in vitro. A: Four websites (miRDB, TargetScan, miRTarBase and RNA22) were used to predict 3 downstream target mRNAs with binding sites for miR-3121-3p; B: HuR expression was assessed in DLD1 and HCT116 cells transfected with miR-3121-3p mimics, miR-3121-3p inhibitor or NC using quantitative real-time polymerase chain reaction and Western blot assays; C and D: miR-3121-3p mimics inhibited cell viability and clonogenicity, but miR-3121-3p inhibitor enhanced cell viability and clonogenicity; E: Upregulation of miR-3121-3p inhibited cell migration and invasion capabilities, whereas downregulation of miR-3121-3p enhanced these capabilities.