Gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid-enhanced magnetic resonance imaging for evaluating fibrosis regression in chronic hepatitis C patients after direct-acting antiviral

Table 2 Clinical characteristics of patients for pre and post sustained virological response

	Pre SVR	Post SVR	Z/t value	P value
ALT (U/L)	55 (29.5)	17 (11)	-4.015	< 0.001
AST (U/L)	40 (29.5)	20 (10.5)	-4.016	< 0.001
TB (μmol/L)	14 (6.5)	15.5 (11.3)	-0.541	0.588
Alb (g/L)	44.90 ± 3.40	47.43 ± 3.06	-3.919	0.001
Platelet (× 109/L)	165 (87)	199 (130)	-2.576	0.01
INR	1.04 ± 0.14	1.02 ± 0.07	0.425	0.675
mHAI score, n (%)			-2.362	0.023
0-4	5 (24)	15 (71)
5-8	10 (48)	4 (9)
13-18	6 (28)	2 (10)
Ishak score, n (%)			-0.370	0.713
0-2	5 (24)	7 (33)
3-4	9 (43)	7 (33)
5-6	7 (33)	7 (33)
APRI	0.58 (1.32)	0.25 (0.40)	-4.015	< 0.001
FIB-4	1.34 (3.61)	0.99 (1.81)	-3.007	0.003
LSM (kpa)	6.6 (7.5)	5.8 (4.0)	-2.746	0.006
CEI	1.65 ± 0.11	1.68 ± 0.16	-1.087	0.29

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; APRI: AST-to platelet ratio index; CEI: Contrast enhancement index; HCV: Hepatitis C virus; INR: International normalized ratio; mHAI: Modified histology activity index; LSM: Liver stiffness measurement; SVR: Sustained virological response; TB: Total bilirubin.