Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach

doi:10.3748/wjg.v28.i2.242

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2022; 28(2): 242-262
Published online Jan 14, 2022. doi: 10.3748/wjg.v28.i2.242

Table 9 Multivariate analysis of genotype frequencies of tumor necrosis factor-alpha-1030 polymorphism and sociodemographic characteristics in Helicobacter pylori infection

Variables		P value	OR (95%CI)
Age		0.946	0.99 (0.98-1.02)
Gender	Male		1 (reference)
Gender	Female	0.845	0.93 (0.42-2.02)
Residence	Urban		1 (reference)
Residence	Rural	0.341	1.46 (0.67-3.18)
Hospital	Private		1 (reference)
Hospital	Public	0.045¹	0.45 (0.21-0.98)
Genotype frequency	T/T		1 (reference)
	T/C	0.016^a	2.87 (1.22-6.78)
	C/C	0.982	1.02 (0.27-3.88)

¹Weak evidence of significant different.

^aP value < 0.05 statistically significant different. OR: Odds ratio; 95%CI: 95% confidence interval.

Citation: Idris AB, Idris AB, Gumaa MA, Idris MB, Elgoraish A, Mansour M, Allam D, Arbab BM, Beirag N, Ibrahim EAM, Hassan MA. Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach. World J Gastroenterol 2022; 28(2): 242-262
URL: https://www.wjgnet.com/1007-9327/full/v28/i2/242.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i2.242