Obesity is associated with decreased risk of microscopic colitis in women

Table 3 Reproductive factors and risk of microscopic colitis in women

	Cases		Controls
	n = 94		n = 176		Crude	Model 11	Model 22
	n	%	n	%	OR (95%CI)	aOR (95%CI)	aOR (95%CI)
Age of menarche
≤ 11	18	20.5	46	30.3	Ref.	Ref.	Ref.
12	24	27.3	36	23.7	1.70 (0.80-3.61)	1.30 (0.53-3.17)	1.41 0.52-3.83)
13	23	26.1	38	25.0	1.55 (0.73-3.28)	0.76 (0.31-1.85)	0.54 (0.20-1.43)
≥ 14	23	26.1	32	21.1	1.84 (0.86-3.94)	0.90 (0.36-2.28)	0.85 (0.30-2.42)
Parity
Nulliparous	15	16.5	29	19.0	Ref.	Ref.	Ref.3
Parous	76	83.5	124	81.1	1.04 (0.88-1.24)	1.02 (0.83-1.25)	1.00 (0.81-1.23)
Number of live births
None	15	16.5	29	19.0	Ref.	Ref.	Ref.3
1	13	14.3	20	13.1	1.26 (0.49-3.20)	1.16 (0.39-3.48)	1.19 (0.40-3.60)
2	42	46.2	60	39.2	1.35 (0.65-2.83)	1.20 (0.50-2.89)	1.15 (0.47-2.81)
3 or more	21	23.1	44	28.8	0.92 (0.41-2.08)	0.78 (0.28-2.16)	0.83-0.30-2.35)
Age of first live birth (among parous women)
≤ 19	13	17.1	32	25.8	Ref.	Ref.	Ref.
20-23	12	15.8	42	33.9	0.70 (0.28-1.75)	0.24 (0.07-0.82)	0.23 (0.07-0.85)
24-29	26	34.2	27	21.8	2.37 (1.02-5.49)	0.76 (0.24-2.43)	0.78 (0.23-2.63)
30+	25	32.9	23	18.6	2.68 (1.13-6.31)	1.07 (0.32-3.58)	1.02 (0.28-3.68)
Oral contraceptives
No	27	29.7	23	15.0	Ref.	Ref.	Ref.
Yes	64	70.3	130	85.0	0.42 (0.22-0.79)	0.38 (0.17-0.84)	0.20 (0.08-0.52)

¹Model 1 Adjusted for age, education and body mass index (BMI).

²Model 2 adjusted for age, education, BMI, age first live birth, number of live births, age of menarche.

³Omitted age of first live birth from model because of collinearity.