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©The Author(s) 2022.
World J Gastroenterol. May 21, 2022; 28(19): 2123-2136
Published online May 21, 2022. doi: 10.3748/wjg.v28.i19.2123
Published online May 21, 2022. doi: 10.3748/wjg.v28.i19.2123
Table 1 Characteristics of non-severe acute pancreatitis and severe acute pancreatitis patients in derivation and validation cohort
Characteristic | Derivation cohort | P value | Validation cohort | P value | ||
non-SAP (n = 327) | SAP (n = 80) | non-SAP (n = 131) | SAP (n = 59) | |||
Age (yr) | 49.0 (36.0; 63.5) | 46.0 (34.8; 62.2) | 0.424 | 40.0 (32.0; 58.5) | 44.0 (38.0; 53.0) | 0.371 |
Female (%) | 131 (40.1) | 27 (33.8) | 0.363 | 63 (48.1) | 14 (23.7) | 0.003 |
Weekend admission (%) | 65 (19.9) | 26 (32.5) | 0.023 | 37 (28.2) | 13 (22.0) | 0.471 |
Etiology (%) | 0.021 | 0.003 | ||||
Biliary | 113 (34.6) | 31 (38.8) | 54 (41.2) | 11 (18.6) | ||
Hypertriglyceridemia | 113 (34.6) | 36 (45.0) | 44 (33.6) | 21 (35.6) | ||
Alcoholic | 27 (8.26) | 7 (8.75) | 5 (3.82) | 8 (13.6) | ||
Others | 74 (22.6) | 6 (7.50) | 28 (21.4) | 19 (32.2) | ||
Peritoneal irritation (%) | 74 (22.6) | 31 (38.8) | 0.005 | 27 (20.6) | 32 (54.2) | < 0.001 |
GCS < 15 (%) | 2 (0.61) | 5 (6.25) | 0.004 | 3 (2.29) | 7 (11.9) | 0.011 |
Tem (℃) | 36.6 (36.4; 37.0) | 37.2 (36.5; 38.2) | < 0.001 | 37.0 (36.8; 37.4) | 38.0 (37.5; 38.4) | < 0.001 |
SBP (KPa) | 17.2 (15.9; 18.7) | 16.4 (14.9; 18.8) | 0.119 | 16.3 (15.2; 18.4) | 16.8 (14.7; 19.5) | 0.949 |
HR (bpm) | 82.0 (76.0; 94.5) | 118 (99.5; 132) | < 0.001 | 89.0 (79.0; 102) | 110 (100; 130) | < 0.001 |
RR (bpm) | 20.0 (18.0; 20.0) | 22.0 (20.0; 28.2) | < 0.001 | 20.0 (18.0; 21.0) | 23.0 (20.5; 29.5) | < 0.001 |
WBC (× 109/L) | 11.6 (8.74; 15.2) | 14.2 (10.2; 18.7) | 0.001 | 12.4 (8.70; 15.6) | 16.4 (12.2; 21.1) | < 0.001 |
HCT (%) | 40.8 (37.5; 44.8) | 43.6 (36.9; 48.4) | 0.022 | 41.3 (37.8; 45.0) | 42.9 (36.5; 49.0) | 0.218 |
PLT (×109/L) | 221 (178; 276) | 192 (156; 274) | 0.03 | 232 (196; 278) | 202 (166; 264) | 0.025 |
K (mmol/L) | 3.90 (3.60; 4.25) | 3.90 (3.50; 4.30) | 0.817 | 3.90 (3.50; 4.10) | 4.00 (3.50; 4.55) | 0.074 |
Na (mmol/L) | 137 (134; 140) | 137 (132; 140) | 0.909 | 137 (133; 140) | 137 (133; 140) | 0.664 |
Ca (mmol/L) | 2.26 (2.13; 2.34) | 1.96 (1.74; 2.16) | < 0.001 | 2.22 (2.08; 2.32) | 1.93 (1.77; 2.10) | < 0.001 |
Cr (μmol/L) | 67.0 (55.0; 80.0) | 90.0 (70.8; 142) | < 0.001 | 61.0 (52.0; 77.0) | 90.0 (62.5; 227) | < 0.001 |
BUN (mmol/L) | 5.00 (3.88; 6.34) | 7.06 (5.26; 10.4) | < 0.001 | 4.66 (3.32; 5.84) | 6.67 (4.91; 14.2) | < 0.001 |
Glu (mmol/L) | 8.00 (6.50; 12.9) | 11.0 (7.45; 16.3) | < 0.001 | 8.70 (6.80; 11.8) | 11.3 (8.05; 17.2) | 0.004 |
Local complication (%) | 104 (31.8) | 73 (91.2) | < 0.001 | 66 (50.4) | 55 (93.2) | < 0.001 |
ICU admission (%) | 12 (3.67) | 37 (46.2) | < 0.001 | 12 (9.16) | 38 (64.4) | < 0.001 |
ICU stays (d) | 0.00 (0.00; 0.00) | 0.00 (0.00; 10.0) | < 0.001 | 0.00 (0.00; 0.00) | 5.00 (0.00; 9.00) | < 0.001 |
Hospital stays (d) | 10.0 (7.00; 14.0) | 17.5 (8.75; 25.0) | < 0.001 | 9.00 (4.00; 15.0) | 23.0 (15.0; 30.0) | < 0.001 |
Mortality (%) | 0 (0.00) | 3 (3.75) | 0.007 | 1 (0.76) | 4 (6.78) | 0.033 |
qSOFA | 0.00 (0.00; 0.00) | 1.00 (0.00; 1.00) | < 0.001 | 0.00 (0.00; 1.00) | 1.00 (0.00; 1.00) | < 0.001 |
SIRS | 1.00 (0.00; 2.00) | 3.00 (2.00; 3.00) | < 0.001 | 1.00 (0.00; 2.00) | 3.00 (2.00; 3.00) | < 0.001 |
BISAP | 1.00 (0.00; 1.00) | 2.00 (2.00; 3.00) | < 0.001 | 1.00 (0.00; 2.00) | 2.00 (2.00; 3.00) | < 0.001 |
- Citation: Li YL, Zhang DD, Xiong YY, Wang RF, Gao XM, Gong H, Zheng SC, Wu D. Development and external validation of models to predict acute respiratory distress syndrome related to severe acute pancreatitis. World J Gastroenterol 2022; 28(19): 2123-2136
- URL: https://www.wjgnet.com/1007-9327/full/v28/i19/2123.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i19.2123