Clinical significance of variant hepatic artery in pancreatic resection: A comprehensive review

Table 2 Surgical outcomes of pancreaticoduodenectomy in patients with and without aberrant hepatic artery (> 50 cases)

Ref.	Total, n	AHA, n	Morbidity, n (%)		POPF, n (%)		PPH, n (%)		DGE, n (%)		Reoperation, n (%)		Mortality, n (%)
			AHA	n-AHA	AHA	n-AHA	AHA	n-AHA	AHA	n-AHA	AHA	n-AHA	AHA	n-AHA
OPD
Rammohan et al[17]	225	43	26 (60.5)	111 (61.0)	2 (4.7)	9 (4.9)	1 (2.3)	4 (2.1)	23 (53.4)	98 (53.8)	NA	NA	1 (2.3)	3 (1.7)
Kim et al[26]	249	371	92 (24.3)	882 (41.5)	1 (2.7)	12 (5.6)	1 (2.7)	16 (7.6)	4 (10.8)	16 (7.6)	NA	NA	0	1 (0.5)
Sulpice3 et al[30]	84	291	14 (48.3)	32 (58.2)	3 (10.3)	9 (16.4)	4 (13.8)	9 (16.4)	10 (34.5)	24 (43.6)	NA	NA	3 (10.3)	3 (5.5)
Eshuis et al[53]	758	143	80 (55.9)	303 (49.3)	18 (12.6)	87 (14.1)	11 (7.7)	44 (7.2)	48 (33.6)	193 (31.4)	10 (7.0)	68 (11.0)	2 (1.4)	13 (2.1)
Mansour3 et al[5]	82	41	22 (53.7)	27 (65.9)	8 (19.5)	12 (29.3)	4 (9.8)	3 (7.3)	6 (14.6)	7 (17.1)	0	0	1 (2.4)	0
Crocetti et al[34]	297	441	32 (72.7)	185 (73.1)	5 (11.3)	27 (10.7)	2 (4.5)	12 (4.7)	5 (11.4)	37 (14.6)	3 (6.8)	28 (11.7)	7 (15.9)	33 (13.0)
Alexakis3 et al[4]	105	35	4 (11.4)	19 (27.1)	2 (5.7)	9 (12.9)	0	2 (2.9)	1 (2.9)	1 (1.4)	1 (2.9)	5 (7.1)	2 (5.7)	4 (5.7)
LPD
Wang et al[7]	576	127	NA	NA	21 (16.5)	68 (15.1)	11 (9.0)	37 (8.2)	3 (2.5)	9 (2.0)	4 (3.1)	24 (5.3)	4 (3.1)	12 (2.7)
Giani et al[25]	72	141	5 (35.7)	34 (58.6)	2 (14.3)	10 (17.2)	2 (14.3)	10 (17.2)	2 (14.3)	14 (24.1)	NA	NA	0	4 (6.9)
Zhang et al[3]	218	54	22 (40.7)	70 (42.7)	5 (2.3)	21 (9.6)	5 (2.3)	15 (6.9)	NA	NA	NA	NA	3 (3.7)	7 (4.3)
RPD
Nguyen et al[31]	142	30	19 (63.3)	74 (66.0)	4 (13.3)	9 (8.1)	NA	NA	3 (10.0)	26 (23.2)	NA	NA	2 (6.7)	3 (2.7)
Kim et al[33]	73	151	5 (33.3)	29 (50.0)	2 (13.3)	5 (8.6)	1 (6.7)	5 (8.6)	NA	NA	2 (13.3)	4 (6.9)	0	2 (3.4)

¹AHA in these studies included only right hepatic artery variants.

²The P value for this comparison was 0.04, while all others were > 0.05.

³These studies provided matched analysis.

AHA: Aberrant hepatic artery; DGE: Delayed gastric emptying; LPD: Laparoscopic pancreaticoduodenectomy; n-AHA: Non-aberrant hepatic artery; NA: Not available; OPD: Open pancreaticoduodenectomy; POPF: Postoperative pancreatic fistula; PPH: Post-pancreatectomy hemorrhage; RPD: Robotic pancreaticoduodenectomy.