Clinical utility of two-dimensional shear-wave elastography in monitoring disease course in autoimmune hepatitis-primary biliary cholangitis overlap syndrome

Table 1 Baseline characteristics of the patients

Characteristic	Value
Gender, female, n (%)	132 (90)
Age, yr	49 (44-55)
BMI (kg/m2)	21.5 (19.6-22.9)
Total bilirubin, μmol/L	36.6 (19.3-72.7)
ALB, g/L	38.7 (34.1-43.7)
PLT, × 109/L	127 (79-185)
ALT, IU/L	100 (63-185)
AST, IU/L	114 (74-177)
ALP, IU/L	342 (194-518)
GGT, IU/L	298 (176-499)
IgG, g/L	20.5 (16.1-24.7)
IgM, g/L	3250 (2023-5095)
LKM, positive, n (%)	0
ANA, positive, n (%)	144/148 (97.3)
AMA, positive, n (%)	89/148 (60.1)
Fibrosis stage, n (%)
S0-S1	25 (15.4)
S2	48 (30.2)
S3	13 (9.9)
S4	62 (44.4)
Activity grade, n (%)
G0-G1	10 (6.8)
G2	53 (35.2)
G3	78 (53.1)
G4	7 (4.9)
LS, kPa	13.6 (9.8-20.6)

Data are presented as median and interquartile range, number (percentage). The reference laboratory parameter value: Total bilirubin: 5-28 μmol/L; alanine aminotransferase < 50 IU/L; aspartate aminotransferase < 40 IU/L; albumin: 40-55 g/L; platelet count: 100-300 × 10⁹/L; alkaline phosphatase: 51-160 IU/L; gamma-glutamyl transpeptidase: < 60 IU/L; immunoglobulin G: 8-15.5 g/L; immunoglobulin M: 700-2200 mg/L. BMI: Body mass index; TB: Total bilirubin; ALB: Albumin; PLT: Platelet count; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; IgG: Immunoglobulin G; IgM: Immunoglobulin M; LKM: Liver-kidney microsomal antibody; AMA: Antimitochondrial antibodies; ANA: Antinuclear antibody; LS: Liver stiffness.