Copyright
©The Author(s) 2022.
World J Gastroenterol. May 14, 2022; 28(18): 1996-2007
Published online May 14, 2022. doi: 10.3748/wjg.v28.i18.1996
Published online May 14, 2022. doi: 10.3748/wjg.v28.i18.1996
Variable | IGBC (n = 58) | NIGBC (n = 32) | P value |
Median age (range) | 63 yr (55.8-71.3) | 66 yr (66.0-71.5) | 0.302 |
Gender | 0.08 | ||
Male | 9 (16) | 10 (32) | |
Female | 49 (84) | 22 (68) | |
Ethnicity | 0.507 | ||
Caucasian | 39 (67) | 23 (72) | |
Asian | 15 (26) | 5 (16) | |
Black | 3 (5) | 2 (6) | |
Missing | 1 (2) | 2 (6) | |
Median BMI (range) | 28.2 (24.3-32.1) | 28.2 (24.2-30.7) | 0.563 |
ASA score | 0.829 | ||
1 | 4 (7) | 2 (6) | |
2 | 43 (74) | 23 (72) | |
3 | 10 (17) | 6 (19) | |
Missing | 1 (2) | 1 (3) | |
Median CCI (range) | 4 (3-5) | 4 (4-6) | 0.635 |
Extent of surgery | < 0.001 | ||
Minor resection | 57 (98) | 24 (75) | |
Major resection | 1 (2) | 8 (25) | |
T stage | < 0.001 | ||
CIS | 1 (2) | 1 (3) | |
T1a | 3 (5) | 0 | |
T1b | 4 (7) | 1 (3) | |
T2 | 42 (72) | 12 (38) | |
T3 | 7 (12) | 15 (47) | |
T4 | 1 (2) | 3 (9) | |
N status | 0.051 | ||
N0 | 41 (71) | 16 (50) | |
N1/2 | 17 (29) | 16 (50) | |
Histologic type | 0.746 | ||
CIS | 1 (2) | 1 (3) | |
Adenocarcinoma | 55 (94) | 30 (94) | |
Adeno-squamous | 1 (2) | 1 (3) | |
Mixed | 1 (2) | 0 | |
Degree of differentiation (CIS excluded) | 0.614 | ||
Well | 7 (12) | 4 (13) | |
Moderate | 30 (52) | 20 (63) | |
Poor | 12 (21) | 5 (16) | |
Undifferentiated/unclassified | 8 (14) | 2 (6) | |
Resection margin | 0.169 | ||
Negative | 53 (91) | 26 (81) | |
Positive | 5 (9) | 6 (19) | |
Cystic duct margin on index cholecystectomy | 6 (10) | N/A | N/A |
Post-operative complications | 15 (26) | 11 (34) | 0.394 |
Pattern of recurrence | 0.628 | ||
Local/regional | 5 (9) | 5 (16) | |
Distant | 6 (10) | 5 (16) | |
Local and distant | 2 (3) | 1 (3) | |
Adjuvant chemotherapy | 12 (21) | 8 (25) | 0.502 |
- Citation: Alarabiyat M, Raza SS, Isaac J, Mirza D, Marudanayagam R, Roberts K, Abradelo M, Bartlett DC, Dasari BV, Sutcliffe RP, Chatzizacharias NA. Incidental gallbladder cancer diagnosis confers survival advantage irrespective of tumour stage and characteristics. World J Gastroenterol 2022; 28(18): 1996-2007
- URL: https://www.wjgnet.com/1007-9327/full/v28/i18/1996.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i18.1996