Clinical outcomes of endoscopic papillectomy of ampullary adenoma: A multi-center study

Table 3 Risk factors of early recurrence

	Simple logistic regression (Univariate analysis)		Multiple logistic regression (Multivariate analysis)
	OR (95%CI)	P value	OR (95%CI)	P value
Age, > 65 yr	4.18 (1.042-16.774)	0.044	3.441 (0.807-14.672)	0.095
Sex, Male	1.8 (0.513-6.319)	0.359
Body mass index > 25 kg/m2	1.286 (0.251-6.587)	0.763
Symptomatic	3.022 (0.851-10.738)	0.087
EUS	3.792 (1.031-13.946)	0.045	1.622 (0.290-9.073)	0.582
Cholangiogram	1.125 (0.307-4.128)	0.859
Pancreatogram	2.338(0.281-19.450)	0.432
Submucosal lifting	3.067 (0.291-32.329)	0.351
Piecemeal resection	1.286 (0.251-6.587)	0.763
Thermal ablation	0.313 (0.038-2.578)	0.280
BDS	1.244 (0.304-5.096)	0.761
PDS	0.901 (0.221-3.675)	0.885
Size, > 15 mm	3.757 (1.048-13.461)	0.042	1.811 (0.344-9.521)	0.483
Initial pathology
Benign	Ref
LGD	0.683 (0.074-6.272)	0.736
HGD	2.333 (0.167-32.584)	0.529
Positive/uncertain resection margin	5.925 (1.610-21.801)	0.007	4.023 (1.088-16.387)	0.048
Complication	2.937 (0.815-10.582)	0.100

OR: Odds ratio; EUS: Endoscopic ultrasound; BDS: Bile duct stent insertion; PDS: Pancreatic duct stent insertion; LGD: Low grade dysplasia; HGD: High grade dysplasia.