Basic Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. May 7, 2022; 28(17): 1781-1797
Published online May 7, 2022. doi: 10.3748/wjg.v28.i17.1781
Table 2 List of up- and down-regulated genes between DLDL-shFOXQ1 and DLD1-shControl with a fold-change ≥ 2.0 or ≤ -2.0 by using epidermal growth factor/platelet-derived growth factor SuperArray
Symbol
Gene information
Fold change (shFOXQ1/shControl)
P value
FOXQ1 binding sites (TSS: -2k_+1k)
PLATPlasminogen activator, tissue-8.010.03753
COL1A1Collagen, type I, alpha 1-5.720.01381
ELK1ELK1, member of ETS oncogene family-5.450.02281
BCAR1Breast cancer anti-estrogen resistance 1-3.970.04792
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2-3.630.01973
NCK2NCK adaptor protein 2-3.510.02376
JUNJun proto-oncogene v-jun-3.430.007712
EGR1Early growth response 1-3.360.016611
LTALymphotoxin alpha (TNF superfamily, member 1)-3.180.07963
PDGFBPlatelet-derived growth factor beta-2.910.18965
STAT3Signal transducer and activator of transcription 3 (acute-phase response factor)-2.490.00386
HB-EGFHeparin-binding EGF-like growth factor-2.190.02783
FN1Fibronectin 1-2.100.00056
FASLGFas ligand (TNF superfamily, member 6)-2.080.202617
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog-2.060.00582
MAP2K1Mitogen-activated protein kinase kinase 1-2.020.02435
AKT3V-akt murine thymoma viral oncogene homolog 3-2.020.144011
FOSFBJ murine osteosarcoma viral oncogene homolog-2.010.04705