LncRNA cancer susceptibility 20 regulates the metastasis of human gastric cancer cells via the miR-143-5p/MEMO1 molecular axis

Figure 5 Cancer susceptibility 20 regulates the miR-143-5p target MEMO1. A: Bioinformatic tools were used to predict the potential target mRNA of miR-143-5p; B: The expression levels of MEMO1 in gastric cancer (GC) from TCGA STAD database; C: MEMO1 expression in 50 pairs of gastric cancer tissues and normal tissue samples; D: Putative miR-143-5p binding sequence and mutation sequence of MEMO1 mRNA were as shown; E: Dual luciferase reporter assays were used to confirm the direct target between miR-143-5p and MEMO1; F: MEMO1 expression was decreased in GC cells transfected by miR-143-5p mimics; G: The correlation analysis between cancer susceptibility 20 (CASC20) and MEMO1 expression in 50 GC tissues; H: MEMO1 expression was decreased after knockdown of CASC20. ^aP < 0.05, ^bP < 0.01 vs control.