LncRNA cancer susceptibility 20 regulates the metastasis of human gastric cancer cells via the miR-143-5p/MEMO1 molecular axis

Figure 3 miR-143-5p served as a target of cancer susceptibility 20 in gastric cancer cells. A and B: Relative cancer susceptibility 20 (CASC20) expression levels in nucleus and cytoplasm of SGC7901 and MGC803 cells; C: The relative expressions of miRNAs in gastric cancer (GC) cells after downregulation of CASC20; D: The expression of miR-143-5p was detected by quantitative real-time polymerase chain reaction in GC cells after transfection with si-CASC20; E: The expression levels of miR-143-5p in GC from TCGA database; F: The detection of CASC20 expression after transfection of miR-143-5p mimics; G: The correlation analysis between miR-143-5p expression and CASC20 expression in 50 GC tissues; H: Bioinformatics presentation of CASC20 and miR-143-5p binding sites; I: The verification of CASC20 and miR-143-5p interaction by luciferase report assay. ^aP < 0.05, ^bP < 0.01 and ^cP < 0.001 vs control.