Copyright
©The Author(s) 2022.
World J Gastroenterol. Apr 28, 2022; 28(16): 1641-1655
Published online Apr 28, 2022. doi: 10.3748/wjg.v28.i16.1641
Published online Apr 28, 2022. doi: 10.3748/wjg.v28.i16.1641
Cancer types | Assessed cancer cell lines | Expression | Related genes and pathways | Biological significance | PMID |
Hepatocellular carcinoma | PLC/PRF/5, Hep3B, HepG2, MHCC97L, Huh7, SMMC-7721, HCCLM3 | Up | miR-128, CD151 | Invasion, EMT, sorafenib resistance | 30132868 |
Hepatocellular carcinoma | HepG2, HCCLM3 | Up | miR-326, SMAD3, ZEB1 | Proliferation, migration, EMT, anti-apoptosis | 31548493 |
Hepatocellular carcinoma | HepG2, HuH-7 | Up | miR-214-3p, ASF1B | 34336642 | |
Acute myeloid leukemia | HL-60,THP-1,KG-1, NB4, MOLM-14 | Up | miR-758-3p, SRGN | Proliferation, anti-apoptosis | 31452272 |
Bladder cancer | 5637,T24 | Up | miR-515-5p, GINS2 | Proliferation, migration, invasion, EMT | 32596993 |
Breast cancer | MCF-7, MD-MBA-453 | Up | miR-330, PKM | Proliferation, mitochondrial metabolism | 31956955 |
Breast cancer | MDA-MB-231, BT-549, MDA-MB-468 | Up | miR-326, ITGA5 Vav2/Rac1 | Viability, migration, invasion, anti-apoptosis | 32495883 |
Breast cancer | MDA-MB-231, MCF-7 | Up | miR-384, HDGF | Proliferation, migration, invasion | 31586299 |
Breast cancer | MCF-7, MDA-MB-231, HCC1937, BT474, SKBr-3 | Up | miR-154-3p, Notch | Proliferation, migration, invasion | 32883233 |
Breast cancer | MDA-MB-231, MCF-7 | Up | miR-186-5p, ZEB1 | Proliferation, migration, invasion | 33594311 |
Breast cancer | MCF-7, MDA-MB-231, MDA-MB-468, BT-474 | Up | miR-326 | Proliferation, migration, invasion | 32945476 |
Cervical cancer | C33A, HeLa, SiHa, CaSki and HCC94 | Up | YAP1 | Proliferation, migration, invasion | 34816392 |
Cervical cancer | SiHa | Up | Proliferation, migration, invasion | 34238747 | |
Cholangiocarcinoma | HCCC9810, QBC939, RBE, HUCCT1 | Up | miR-3173–5p, ERG | Proliferation, migration, invasion | 34647226 |
Clear cell renal cell carcinoma | ACHN, A498, Caki-1 | Up | miR-139-5p, TOP2A | Proliferation, migration, invasion | 31505165 |
Colorectal cancer | HCT116, LoVo, SW480, and SW620 | Up | miR-539, RUNX2 | Proliferation, migration, invasion | 32187965 |
Colorectal cancer | HT29, HCT116, SW480, and LoVo | Up | miR-182-5p, c-Myc | Proliferation, migration, invasion | 28731158 |
Colorectal cancer | SW480, SW620, HCT8, HT29 | Up | miR-370-5p, EZH1 | Proliferation, migration, invasion | 34661273 |
Esophageal cancer | KYSE-150, Eca-9706 | Up | miR-186-5p, METTL3, m6A | 33596916 | |
Gastric cancer | MGC-803, AGS, BGC-823, SGC-7901, MKN-45, HGC-27 | Up | EZH2, MED18 | Proliferation, migration, invasion | 31534128 |
Gastric cancer | SGC7901, BGC823 | Up | IL-6, STAT3, SNHG3, miR-3619-5p, ARL2 | Proliferation | 32930970 |
Gastric cancer | HGC-27, GC9811-P | Up | miR-326, TWIST | Proliferation, migration, invasion | 34257656 |
Glioma | A172, SHG44 | Up | miR-384, HDGF | Proliferation, migration, invasion, anti-apoptosis | 33817254 |
Glioma | U-87-MG, U-251-MG | Up | miR-485-5p, LMX1B | Proliferation, migration, invasion | 34153159 |
Laryngeal carcinoma | 16HBE, TU212, TU686 | Up | miR-384, WEE1 | Proliferation, migration, invasion | 31238052 |
Laryngeal carcinoma | TU177, AMC-HN-8 | Up | Wnt/β-catenin, miR-340-5p, YAP1 | Proliferation, migration, anti-apoptosis, mitochondrial metabolism | 32538668 |
Lung adenocarcinoma | A549, H1299 | Up | Proliferation, cell cycle,anti-apoptosis | 30154938 | |
Lung adenocarcinoma | A549, H1299, H1975 | Down | miR-890 | Anti-proliferation, anti-migration, anti-invasion, apoptosis | 34306585 |
Non-small-cell lung cancer | H1299, H358, A549, H1975 | Up | miR-13433p, NFIX | Proliferation, migration, invasion | 34132359 |
Non-small-cell lung cancer | CMT-167, LLC, CMT-170, CMT-181 | Up | TGF-β pathway, IL-6, JAK2, STAT3 pathway | Proliferation, migration, EMT | 31602642 |
Non-small-cell lung cancer | SPC-A1, A549, NCI-H23, NCI-H460 | Up | miR-340-5p | Lymph node infiltration, distant metastases | 33225676 |
Non-small-cell lung cancer | A549, H322, H1299, GLC-82, SPC-A1 | Up | miR-216a, ZEB1 | Proliferation, migration, invasion | 33177840 |
Non-small-cell lung cancer | A549, HCC827, H2170, H520 | Up | miR-515-5p, SUMO2 | Proliferation, migration, invasion, EMT | 34032148 |
Oral squamous cell carcinoma | SCC4, CAL-27 | Up | miR-2682-5p, HOXB8 | Proliferation, migration | 32989886 |
Oral squamous cell carcinoma | SCC-15, SCC-9, CAL-27, HN5 | Up | Wnt/β-catenin, NFYC | Proliferation, migration | 31762107 |
Osteosarcoma | Saos2, MG63, U2OS, HOS | Up | miR-151a-3p, RAB22A | Proliferation, migration, invasion | 30797154 |
Osteosarcoma | MG-63, 143B, HOS, SW-1353, Saos-2, U-2OS | Up | miR-196a-5p | Proliferation, colony formation | 30791797 |
Ovarian cancer | SK-OV3, TOV-21G, and OVCAR-3 | Up | Energy metabolism | 29921511 | |
Ovarian cancer | SKOV3, HeyA8, A2780 | Up | miR-339-5p, TRPC3 | Proliferation, anti-apoptosis | 33149611 |
Ovarian cancer | SKOV3, 60OVCAR3, A2780, ES2 | Up | GSK3β/β-catenin | Proliferation, migration | 29758922 |
Ovarian cancer | A2780, SKOV3, OVCAR3, OV90 | Up | miR-139-5p, Notch1 | Proliferation, migration | 33552243 |
Papillary thyroid carcinoma | BCPAP, TPC-1 | Up | miR-214-3p, PSMD10 | Migration, invasion, proliferation, and colony formation | 32048306 |
Prostate cancer | PC3, DU145, 22RV1, NCaP | Up | miR-577, SMURF1 | Proliferation, migration, EMT, anti-apoptosis | 32248648 |
Prostate cancer | PC3, 22RV1, DU145, LNCaP | Up | miR-487a-3p,TRIM25 | Viability, migration, invasion, EMT | 33416420 |
- Citation: Shan DD, Zheng QX, Wang J, Chen Z. Small nucleolar RNA host gene 3 functions as a novel biomarker in liver cancer and other tumour progression. World J Gastroenterol 2022; 28(16): 1641-1655
- URL: https://www.wjgnet.com/1007-9327/full/v28/i16/1641.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i16.1641