Prognostic factors of recurrent intrahepatic cholangiocarcinoma after hepatectomy: A retrospective study

Table 2 Multivariate analysis of prognostic factors after intrahepatic cholangiocarcinoma recurrence following hepatectomy

Factors	Multivariate analysis
	HR	95%CI	P value1
Age (≥ 65 yr)	2.12	0.88-5.12	0.096
Alcohol consumption (Yes)	4.64	1.53-14.04	0.007
CA19-9 (≥ 200 U/mL) (initial)	2.63	0.94-7.35	0.065
Histological grade (PD)	1.18	0.59-2.35	0.646
Biliary invasion (Yes)	1.04	0.41-2.63	0.940
Vascular tumor thrombus (Yes)	1.80	0.70-4.65	0.222
DFS (< 6 mo)	3.47	1.59-7.60	0.002
CA19-9 (≥ 200 U/mL) (recurrence)	1.13	0.47-2.71	0.785
Treatment after recurrence (Yes)	0.21	0.08-0.55	0.001

¹Data are based on Cox regression model.

CI: Confidence interval; CA19-9: Serum carbohydrate antigen 19-9; PD: Poor-differentiated; DFS: Disease free survival.